Medicine dosing to reduce bleeding in nose surgery
This study looks at using a medicine called tranexamic acid (which helps reduce bleeding) during nose surgery, along with a precise way of giving another pain medicine (remifentanil) to keep you comfortable and stable. The goal is to find the best dose to reduce bleeding and improve recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are having elective (planned) septorhinoplasty, a nose operation to fix breathing and shape, under general anesthesia.
- Your surgery will last between 1 and 4 hours (60-240 minutes).
- You have no history of blood clots, bleeding disorders, or conditions that prevent taking tranexamic acid.
- You do not regularly use strong painkillers, sedatives, or tranquilizers.
- You do not have severe heart, kidney, or liver disease, uncontrolled high blood pressure, or significant irregular heartbeat.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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