Comparing two blood pressure medicines during planned nasal surgery
Treatments studied
Part of Ear, nose & throat clinical trials.
This study compares two medicines used during nasal surgery to keep blood pressure stable and reduce bleeding. One is a short-acting painkiller (remifentanil), and the other is a blood pressure-lowering drug (nicardipine). If you are having planned nasal surgery eliminated for participation, you might be eligible.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are scheduled for planned (not emergency) nasal surgery.
- You are in good overall health with no serious heart, lung, kidney, or liver conditions.
- You are not regularly taking blood pressure medications (like beta-blockers or calcium channel blockers).
- You are not allergic to remifentanil or nicardipine.
- You are not pregnant or breastfeeding, and your weight is under a BMI of 35.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a combination of two medications helps keep blood pressure steady and reduces bleeding during ear, nose, or throat surgery. It is comparing giving just one pain medication versus the pain medication plus a blood pressure-lowering drug.
This trial tests two sedative medicines to see which one controls blood pressure better during sinus surgery, which may reduce bleeding and improve the surgery's outcome.
This study looks at how different blood pressure targets during nose surgery affect blood flow to the eye and the optic nerve. It aims to find the safest way to protect eye health during anesthesia.
This trial compares two commonly used blood-pressure medicines—atenolol and metoprolol—to see which one works best for keeping blood pressure safely low during nasal surgeries. It may help patients have more stable anesthesia while reducing side effects from blood pressure changes.
This trial tests if adding a second medicine, ketamine, to dexmedetomidine helps control blood pressure better during ear or nose surgery. It may lead to safer and smoother anesthesia for patients needing controlled low blood pressure.
This trial tests whether noradrenaline is better than standard care for preventing dangerously low blood pressure during surgery. If you are having non-cardiac surgery that lasts at least an hour and are expected to stay overnight, this study may be for you.
Hear when a new Nasal Surgery trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.