Observational study of septic shock management
Part of Infections clinical trials.
This study tracks how doctors treat septic shock in the ICU to learn what works best. If you have septic shock, joining this study helps researchers understand which treatments are most effective, and you'll get the same care you would anyway.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years old or older.
- You need to be in the intensive care unit (ICU) for this study.
- You must have septic shock, which means you have an infection and need medicine to keep your blood pressure up, along with high lactate levels (a sign of poor oxygen flow).
- You cannot already be in the ICU when the study starts (but you can join if you were in ICU before).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial checks if measuring the carbon dioxide gap (a sign of how well blood is flowing to organs) can help doctors improve treatment for people in septic shock. Septic shock is a severe infection that causes very low blood pressure and organ damage.
This study looks at the bacteria in the gut of patients with sepsis in the ICU. It aims to understand how these bacteria change during critical illness, which could lead to better treatments.
This study tests if giving fewer fluids (other than the fluids to keep blood pressure up) can help people recover from septic shock. It compares a reduced fluid strategy to the usual care in the ICU.
This study looks at how the body uses energy (metabolism) in people with septic shock. It collects information from standard monitoring during a fluid challenge (a small IV fluid test) to find patterns that might help doctors better understand and treat septic shock.
This trial tests a new approach to treating septic shock, a life-threatening condition where infection causes dangerously low blood pressure. It aims to see if a different way of managing fluids and medications can improve recovery compared to standard care.
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