CT-FFR guided heart treatment for severe aortic stenosis
Part of Heart & circulation clinical trials.
This trial tests whether using a special CT scan (CT-FFR) to guide treatment improves outcomes for people with severe aortic stenosis (a narrowed heart valve). It may help doctors decide between valve replacement surgery or a less invasive procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are over 18 years old.
- You have severe aortic stenosis, confirmed by an ultrasound of your heart.
- You have symptoms like shortness of breath, chest pain, or fatigue that limit your activity.
- You are a candidate for both a minimally invasive valve replacement (through a leg artery) and open-heart surgery to replace the valve.
- You are willing to have a special CT scan of your heart arteries before the procedure.
- You have no allergies to the valve materials or the dye used in CT scans.
- You have not had a heart valve replacement or bypass surgery before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new valve device placed through a small tube (catheter) to treat severe aortic stenosis, a condition where the aortic valve is narrowed and doesn't open fully. It's for patients who cannot have traditional open-heart surgery.
This study checks whether an “investigational” transcatheter aortic valve is safe and works well for people with severe, calcified aortic stenosis (a stiff, narrowed heart valve). It may help improve valve function and symptoms, but you must meet specific heart, scan, and health-status requirements.
This trial compares two approaches for replacing a tight aortic heart valve (TAVI) through a leg artery: doing it with or without a routine check of your heart's arteries (coronary angiogram). If you have severe aortic stenosis and are scheduled for TAVI, this study helps find out whether skipping the artery check is safe and effective.
This study uses a CT scan plus a personalized computer model to plan a less invasive valve replacement (TAVR). It may help doctors better prepare for the procedure using simulation before your valve is placed.
This trial studies whether a new through-the-blood-vessel heart valve (TAVR) is safe and works well for people with severe aortic stenosis who are too risky for traditional surgery. If you qualify, you would be closely followed to check your symptoms and valve function over time.
This trial compares different methods to evaluate coronary artery disease in patients planning to have a transcatheter aortic valve replacement (TAVR) for severe aortic stenosis. The goal is to find out if a less invasive approach is as safe and effective as the standard one.
Hear when a new Severe Aortic Stenosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.