Vorasidenib guided by AGX PET for recurrent low-grade glioma
Part of Cancer clinical trials.
This trial tests a targeted drug, vorasidenib, for people with a specific type of slow-growing brain tumor (low-grade glioma) that has come back or is still present after surgery. The drug is guided by a special PET scan to see if it reaches the tumor.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a slow-growing brain tumor (grade 2 or 3) with a specific gene mutation (IDH1 or IDH2)
- Your tumor has come back or is still there after surgery, and shows up on an MRI scan as a visible spot (at least 1 cm)
- You are 18 years or older
- You have a good performance status (able to care for yourself, score 80 or above on a standard scale)
- You have not had chemotherapy, radiation, or other IDH-blocking drugs before
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests the drug vorasidenib for people with a slow-growing brain tumor (Grade 2 glioma) that has an IDH mutation. The goal is to see how well the drug works and how it affects your quality of life.
This study tests a new drug called safusidenib for people with IDH1-mutant gliomas (a type of brain tumor) that kept growing even while on the previous drug vorasidenib. The goal is to see if it can control the tumor safely and effectively.
This study asks patients with a specific type of low-grade brain tumor (IDH mutant grade 2 glioma) to share their experiences and quality of life while receiving a treatment called vorasidenib, with or without radiation. Your feedback helps doctors understand how well the treatment works from your perspective.
This Phase 3 trial tests safusidenib, a targeted medicine, to help stop or slow the return of certain brain tumors with an IDH1 mutation. It focuses on people after initial treatment (surgery and/or radiation and temozolomide), aiming to improve outcomes during maintenance therapy.
This trial tests a combination of two drugs—APG-157 (an oral plant-based medicine) and bevacizumab (Avastin)—for people with recurrent high-grade brain tumors that have already been treated with standard therapies. The goal is to see if adding APG-157 can help control the tumor better.
This trial studies an oral drug called vorasidenib for children and teens with a slow-growing brain tumor (Grade 2 astrocytoma or oligodendroglioma) that has an IDH1 or IDH2 mutation. The drug is taken daily and may help keep the tumor from growing, avoiding the need for immediate chemotherapy or radiation.
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