PARP inhibitor with or without anti-angiogenesis drug for ovarian cancer
Treatments studied
Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.
This trial tests whether adding a drug that blocks blood vessel growth (angiogenesis inhibitor) to a PARP inhibitor works better than the PARP inhibitor alone for ovarian, fallopian-tube, or peritoneal cancers that have a specific DNA repair problem called HRD. It aims to find a more effective treatment for people with these cancers.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have been diagnosed with high-grade serous or endometrioid ovarian, fallopian-tube, or primary peritoneal cancer.
- You are generally in good health, able to carry out daily activities (ECOG 0 or 1).
- Your cancer has a specific genetic feature called homologous recombination deficiency (HRD).
- You are able to undergo a diagnostic laparoscopy or surgery to remove the cancer.
- You do not have any other active cancer, and you are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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