Clin2
NCT07473167Possibly a fitRecruiting

Study of TC011 for large B-cell lymphoma that has not responded to treatment

Relapsed Large B-cell LymphomaRefractory Large B-cell LymphomaDiffuse Large B-cell Lymphoma (DLBCL)High-grade B-cell Lymphoma (HGBL)Transformed Follicular Lymphoma (TFL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This trial tests whether the experimental drug TC011 can help adults with a type of B-cell lymphoma that has come back or stopped responding after at least two rounds of chemotherapy. The study checks for safety and whether the treatment can shrink tumors.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
98 people
Ages
19 years and older
Study type
Interventional

Who can take part

  • You must be 19 years or older
  • You must have large B-cell lymphoma that has returned or not improved after at least two previous treatments
  • You must have at least one tumor that is 1.5 cm or larger on a scan
  • Your heart must pump at least 40% of blood out each beat (measured by LVEF)
  • You must be well enough to undergo a procedure called leukapheresis, where white blood cells are collected
  • You cannot have had certain prior therapies like CAR T-cell therapy or a stem cell transplant from a donor

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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