Clin2
NCT07473375Possibly a fitRecruiting

Factors affecting portal vein clot reopening in cirrhosis

Portal Vein ThrombosisCirrhosisPortal Hypertension Related to CirrhosisPortal Hypertension, Noncirrhotic

Part of Digestive system clinical trials.

This study looks at factors that help open up blood clots in the main vein to the liver (portal vein) in people with cirrhosis and varices. It might help guide treatment to improve blood flow.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
1,500 people
Ages
18 years to 80 years
Study type
Observational

Who can take part

  • You have cirrhosis and a doctor has seen swollen veins in your esophagus or stomach (varices) during an endoscopy.
  • You have a blood clot in the portal vein (the main vein to your liver) confirmed by a CT scan.
  • You do not have liver cancer or any other cancer outside the liver.
  • You have not had a liver transplant or a TIPS procedure (a stent in the liver).
  • You are not taking blood thinners? (Information about anticoagulation therapy is needed.)
  • You do not have a condition called cavernous transformation of the portal vein (a network of small veins that form around a blocked portal vein).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07422701Not yet recruiting
Blood clots in the liver's main vein in cirrhosis

This study is following people with cirrhosis to see how often they get a blood clot in the liver's main vein (portal vein) and whether using blood thinners helps. If you have cirrhosis, joining this study could help doctors learn better ways to prevent and treat these clots.

Beijing, Beijing Municipality
NCT06122753Not yet recruiting
Early TIPS for variceal bleeding with portal vein clot

This study tests whether placing a TIPS (a small tube in the liver to improve blood flow) early after a variceal bleed helps people with cirrhosis and a partial portal vein clot. It may reduce the risk of re-bleeding and improve outcomes.

Chengdu, Sichuan
NCT06513780Recruiting
Liver transplant and portal vein blood clot study

This study looks at how blood clots in the portal vein (the main vein to your liver) affect recovery and outcomes after a liver transplant. If you've had a liver transplant, your data may help doctors understand this better.

Beijing
NCT06669806Recruiting
TIPS Stent Graft for Cirrhosis Complications

This study tests a TIPS stent graft (a tiny mesh tube placed in the liver to relieve pressure) for people with cirrhosis and complications like bleeding or fluid buildup. It aims to see how well it works and if it's safe.

Changsha, Hunan
NCT07390344Recruiting
Study of VIATORR TIPS device for liver pressure

This study tests a new version of a device (VIATORR TIPS) that helps lower high blood pressure in the liver for people with cirrhosis. The device is placed to create a small channel that reroutes blood flow and reduces pressure.

Atlanta, Georgia
NCT06818279Not yet recruiting· Phase 2/Phase 3
Blood thinners for liver vein clot in cirrhosis

This trial tests whether a pill (dabigatran) or a daily injection (enoxaparin) is better at preventing new blood clots in the liver vein for people with cirrhosis. Both are blood thinners, and the study wants to see which one is safer and more effective.

New Delhi, National Capital Territory of Delhi

Hear when a new Portal Vein Thrombosis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.