Preventing joint damage in early psoriatic arthritis
Treatments studied
Part of Bones, joints & muscles, Skin clinical trials.
This trial tests if a treatment can prevent joint damage in people recently diagnosed with psoriatic arthritis. It compares a standard medication (methotrexate) with or without a newer biologic drug (adalimumab) to see which is better at stopping the disease from causing lasting harm.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have had psoriatic arthritis symptoms for 2 years or less
- You have joint pain and swelling (at least one tender and one swollen joint) even after trying anti-inflammatory drugs for 4 weeks
- You have at least one risk factor for worse disease, like many affected joints, signs of joint damage on scans, high inflammation in blood tests, dactylitis (whole finger or toe swelling), nail changes, or difficulty with daily tasks
- You do not have severe deformities in your hand joints
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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