Clin2
NCT06913907Possibly a fitRecruiting

Methotrexate injection for new rheumatoid arthritis patients

Rheumatoid Arthritis (RA)

Treatments studied

Part of Bones, joints & muscles, Immune system & allergy, Skin clinical trials.

This study tests a methotrexate injection (given under the skin) for people with moderate to severe rheumatoid arthritis who haven't taken methotrexate before. Researchers want to see how the medicine builds up in your body and if it helps control your symptoms.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
100 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have not taken methotrexate before (any form, pill or injection).
  • You are 18 years or older.
  • Your rheumatoid arthritis is considered moderate to severe (active joint swelling and pain).
  • You have not used any biologic drugs (like Humira) or JAK inhibitors (like Xeljanz) for RA.
  • You are able to have regular check-ups and blood tests during the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07463937Recruiting
Study of Methotrexate Injections in Rheumatoid Arthritis

This study looks at how well methotrexate injections work in people with rheumatoid arthritis. It is designed for patients who are starting or changing to this type of methotrexate treatment.

Beijing, Beijing Municipality
NCT06726096Enrolling by invitation· Phase 3
Trial of VDJ001 for moderate to severe rheumatoid arthritis

This trial tests a new medicine called VDJ001 for people with moderate to severe rheumatoid arthritis who are already taking methotrexate. The goal is to see if VDJ001 helps reduce joint pain and swelling better than a placebo.

Beijing, Beijing Municipality
NCT06724952Not yet recruiting· Phase 4
Silymarin supplement for rheumatoid arthritis with methotrexate

This trial tests whether adding silymarin (a natural supplement from milk thistle) to standard methotrexate treatment can improve symptoms of rheumatoid arthritis. It may help reduce joint pain and swelling for people who are not yet in remission.

Al Mansurah
NCT07564154Recruiting· Phase 1
Testing KT502 injections for active rheumatoid arthritis

This is an early-stage study testing a new injectable treatment called KT502 for people with moderate-to-severe rheumatoid arthritis (RA) that hasn't responded well to standard treatments. The study will check if the medication is safe and how the body responds to it.

Bayswater, Victoria
NCT07636057Not yet recruiting· Phase 4
Comparing two arthritis pills added to methotrexate

This study compares two oral medications, tofacitinib and upadacitinib, when added to methotrexate for people with rheumatoid arthritis. The goal is to see which one works better and is safer for controlling symptoms.

NCT06641128Not yet recruiting· Phase 4
Empagliflozin with methotrexate for rheumatoid arthritis

This trial tests whether adding empagliflozin to methotrexate helps reduce rheumatoid arthritis activity compared to methotrexate alone. It may protect joints from further damage.

Al Mansurah

Hear when a new Rheumatoid Arthritis (RA) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.