Can psilocybin help treat loss of pleasure?
Treatments studied
Part of Brain & nervous system clinical trials.
This trial tests if psilocybin, a psychedelic substance, can improve the ability to feel pleasure (anhedonia) in people with depression who are not taking antidepressants. It also includes healthy volunteers as a comparison group.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 55 years old.
- You are right-handed.
- Your BMI is between 18.5 and 24.9.
- You are not taking any psychiatric medications, including antidepressants.
- You have a major depressive episode with loss of pleasure, or you are a healthy volunteer.
- You have no history of neurological disease, substance dependency, or severe medical illness.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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