Growth and hormones after stem cell transplant in children
Part of Blood & lymphatic, Hormones & metabolism clinical trials.
This study looks at how children who had a stem cell transplant before puberty grow and develop hormones compared to children who had chemotherapy but no transplant. It aims to understand any long-term effects on growth and puberty.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You were treated for childhood cancer between 2005 and 2020, either with or without a stem cell transplant.
- You had not started puberty at the time of your cancer treatment (for transplant group) or at the time of diagnosis (for non-transplant group).
- Your chemotherapy included at least one of these drugs: cyclophosphamide, ifosfamide, procarbazine, cisplatin, carboplatin, melphalan, thiotepa, busulfan, or treosulfan.
- You entered puberty naturally without needing hormone replacement therapy (like testosterone or estrogen).
- You had follow-up care at a specific clinic in Bologna, Italy, to track your growth until puberty ended.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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