Clin2
NCT07501455Likely a fitRecruiting

Studying toothpaste and mouth rinse effects on gum inflammation

MicrobiomeCytokinesPlaqueGingivitisGingival Bleeding

Part of Infections, Mouth & dental clinical trials.

This study tests whether using a certain toothpaste and mouth rinse can reduce gum inflammation (gingivitis) better than brushing alone. It is for people with mild to moderate gum disease who have not used tobacco or certain medications recently.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
250 people
Ages
18 years to 60 years
Study type
Interventional

Who can take part

  • You must have at least 18 natural teeth (not counting wisdom teeth).
  • You must have gingivitis, which means your gums bleed when gently probed and show signs of inflammation.
  • You must be in generally good health and not have conditions like diabetes or severe gum disease (periodontitis).
  • You cannot smoke, vape, or use any tobacco or cannabis products.
  • You cannot be taking certain medications like antibiotics, steroids, or anti-inflammatory drugs (except low-dose aspirin).
  • If you are able to become pregnant, you must use birth control and not be pregnant or planning pregnancy.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07614490Recruiting· Phase 4
Dental plaque and gum health study

This research study examines how dental plaque relates to gum inflammation in people with different levels of gum health. Researchers will collect plaque samples and measure gum health to better understand these patterns, which may help improve oral care products.

Fort Wayne, Indiana
NCT07842042Recruiting
Toothpaste study for gum health

This study tests a toothpaste with stannous fluoride to see how it affects gum health by measuring certain markers in the fluid around the teeth. It may help reduce gum inflammation and improve oral hygiene.

Birmingham
NCT07816406Not yet recruiting
Toothpaste for plaque and gum health

This study tests a new toothpaste to see how well it removes plaque and reduces gum inflammation (gingivitis). If you have early gum problems, this may help improve your oral hygiene.

Shanghai, Shanghai Municipality
NCT07494747Recruiting
Toothpaste for sensitive gums

This trial tests a toothpaste for people with sensitive, inflamed gums (gingivitis). It looks at how well the toothpaste reduces gum bleeding and plaque.

Castelldefels, Barcelona
NCT07414173Recruiting· Phase 4
Mouthrinse for plaque and gum health

This study tests whether a special antimicrobial mouthrinse can reduce plaque buildup and improve gum health over 6 months. If you have early gum disease (gingivitis) and are generally healthy, this trial may be a good fit.

Schenefeld
NCT07256743Recruiting· Phase 2
Testing a probiotic drink for gum health in healthy adults

This trial tests if taking a daily probiotic drink can help keep gums healthy in people without gum disease. You would be asked to stop using certain dental products during the study.

Toronto, Ontario

Hear when a new Microbiome trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.