Low-dose chemo to prevent relapse in high-risk DLBCL patients
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial tests a low-dose chemotherapy pill (chidamide) for people with a certain high-risk type of DLBCL that still has signs of cancer in the blood after initial treatment. The goal is to keep the cancer from coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a specific type of DLBCL called 'double-expressor lymphoma' (high MYC and BCL2 proteins).
- You must be in complete remission after your first round of chemotherapy.
- You must have a positive blood test for minimal residual disease (MRD), meaning tiny traces of cancer DNA are still detectable.
- You must be between 18 and 80 years old.
- You must have an ECOG performance status of 0, 1, or 2 (able to care for yourself up to mostly bedridden).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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