Oxygen monitoring to guide blood transfusions in intensive care
Part of Blood & lymphatic clinical trials.
This study tests a more precise way to decide when to give red blood cell transfusions to ICU patients with mild anemia. It uses a measurement called ScvO2 (a marker of how well your body is using oxygen) to see if a transfusion is needed, which may help avoid unnecessary transfusions.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be in an intensive care unit (ICU) for medical, surgical, or trauma care.
- Your hemoglobin (a protein in red blood cells that carries oxygen) must be between 7 and 9 grams per deciliter.
- Your circulation must be stable — meaning your blood pressure is okay, lactate level is low, and you don't need high or increasing doses of blood pressure medication.
- You need a central venous catheter (a special IV) and an arterial line, and your urine output is monitored hourly.
- Your breathing must be stable — either no support, or oxygen via nasal prongs or mask, or a ventilator with specific settings.
- You must not have severe kidney, liver, or heart failure, and you must not be pregnant, actively bleeding, have a fever, or require high oxygen support.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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