Clin2
NCT06560164Possibly a fitRecruiting

Comparing blood transfusion levels in ECMO patients

TransfusionRed Blood CellExtracorporeal Membrane OxygenationAnemiaECMO

Part of Blood & lymphatic clinical trials.

This trial tests whether giving more or fewer red blood cell transfusions is better for adult patients on ECMO (a machine that helps your heart and lungs work). The goal is to find the best transfusion approach to improve outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
526 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You must be on ECMO (a heart-lung support machine).
  • You must be able to receive blood products (like blood transfusions).
  • You cannot have refused blood transfusions for any reason (like religious beliefs).
  • You must have started ECMO within the last 48 hours when you are screened.
  • You must be expected to survive at least 24 hours.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05699005Recruiting· Phase 1
Personalized or standard blood transfusion during heart-lung machine

This trial tests whether giving blood in a personalized way, instead of a standard approach, is better for people on a heart-lung bypass machine (VA-ECMO) for heart-related shock. It may help find a safer blood transfusion strategy while you are critically ill.

Lille, NORD
NCT04754854Recruiting
Testing less blood recirculation during veno-venous ECMO

This trial studies whether a change in how a veno-venous ECMO machine works can reduce “blood recirculation” (blood returning to the circuit too quickly) in people with severe lung failure. It may help improve oxygen levels in adults whose ARDS is not responding to standard treatment.

Berlin
NCT07671469Not yet recruiting
Personalized blood transfusion plan for heart surgery patients

This study tests whether a personalized plan for when to give blood transfusions works better than the usual approach in people having heart surgery with a heart-lung machine. The goal is to find a safer and more effective way to manage transfusions during recovery.

Palo Alto, California
NCT07509203Not yet recruiting
Smarter transfusions for ICU patients with anemia

This trial tests if using a specific oxygen measurement (ScvO2) helps guide red blood cell transfusions more safely in ICU patients with moderate anemia. It aims to avoid unnecessary transfusions while ensuring enough oxygen reaches your tissues.

Budapest
NCT05814094Recruiting
Testing a red blood transfusion approach during ECMO

This study looks at whether giving red blood cell transfusions in a specific way is practical and safe for people receiving ECMO (a heart-lung support machine). It’s mainly a feasibility study, meaning the goal is to see if the plan can be carried out smoothly and safely.

Camperdown, New South Wales
NCT06526533Recruiting· Phase 3
Red blood cell transfusion thresholds for ECMO patients

This trial is testing whether a higher or lower threshold for red blood cell transfusions is better for people on ECMO (a heart-lung machine). It aims to find the safest way to manage transfusions during ECMO treatment.

Camperdown, New South Wales

Hear when a new Transfusion trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.