New method to measure mitochondrial DNA in muscle fibers
Part of Hormones & metabolism clinical trials.
This study looks at a new way to measure mitochondrial DNA in muscle fibers. It may help people who have a suspected mitochondrial disorder and a genetic change of uncertain significance.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have symptoms or tests that suggest a problem with your mitochondria (the energy parts of your cells).
- You need to have a mitochondrial DNA change that doctors aren't sure about yet.
- A muscle biopsy must show at least 5 fibers that don't stain for a certain enzyme (COX-negative).
- Your muscle biopsy slides must be available for the researchers to review.
- You or your legal guardian must sign a consent form.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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