Nicorandil to reduce inflammation in active rheumatoid arthritis
Treatments studied
Part of Bones, joints & muscles clinical trials.
This study tests whether nicorandil, a heart medication with anti-inflammatory properties, can help reduce joint inflammation and swelling in people with active rheumatoid arthritis who are already taking conventional disease-modifying drugs. The goal is to see if it provides additional relief from symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have active rheumatoid arthritis (your disease is not in remission, measured by a disease activity score greater than 2.6)
- You are currently taking conventional DMARDs (disease-modifying antirheumatic drugs, standard RA medications)
- You do not have heart disease, diabetes, active infections, or other serious illnesses besides RA
- Your kidney and liver function are normal or only mildly impaired
- You are not taking biological DMARDs (newer injectable or infusion RA medications like biologics)
- You are not taking high-dose oral steroids (more than 15 mg of prednisolone per day)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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