Understanding Moyamoya Disease Risk in Families
Part of Brain & nervous system, Heart & circulation clinical trials.
This study investigates moyamoya disease, a rare condition where blood vessels in the brain narrow over time. Researchers want to identify genetic and early warning signs by studying people diagnosed with the disease, their blood relatives, and healthy volunteers.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must fit into one of three groups: diagnosed with moyamoya disease, a first-degree relative (parent, child, or sibling) of someone with moyamoya disease, or a healthy control with no family history
- If you're in the relative group, you cannot have had a stroke or other brain blood vessel events before joining
- You must be able to complete MRI scans and have no metal implants that would interfere with MRI
- You must be willing and able to attend follow-up appointments over time
- You cannot have serious infections, advanced cancer, severe kidney or liver disease, or active lupus
- You cannot be pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial follows people with moyamoya disease who are treated with medication only, and it also looks at first-degree relatives. The goal is to understand long-term outcomes and whether careful conservative care is beneficial over time.
This study looks at how Moyamoya disease changes over time and what predicts outcomes. It uses approved brain imaging and, likely, thinking/memory tests to understand prognosis.
This study looks at why some people with moyamoya disease have trouble with thinking and memory. It may help find better ways to understand and treat these problems.
This study uses advanced MRI scans to better predict the risk of bleeding in people with moyamoya disease, a rare condition where brain arteries narrow. It aims to improve prevention of bleeding strokes.
This study is building a tool to predict how people with moyamoya disease will do after brain surgery to improve blood flow. If you are an adult with moyamoya and are scheduled for this surgery, you may be able to help.
This study tests if statins (cholesterol-lowering drugs) can help people with Moyamoya disease. The trial will follow patients who receive either surgery or standard care to see if adding a statin improves outcomes.
Hear when a new Moyamoya Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.