Can gut medicine improve blood thinning in heart patients?
Treatments studied
Part of Heart & circulation clinical trials.
This study tests whether a medicine called rifaximin, which targets bacteria in the gut, can make your blood thinner (ticagrelor) work better, reducing the risk of blood clots. If your platelets are still too sticky even on ticagrelor, this treatment might help lower that risk.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You had a heart attack or unstable angina 1 to 12 months ago.
- You are currently taking ticagrelor (Brilinta) 90 mg twice a day for your heart.
- Your blood test shows your platelets (clot-forming cells) are still too active despite the medicine.
- You have not used antibiotics, probiotics, or steroid medicines in the last 3 months, and you have no serious gut conditions like Crohn's disease or bowel blockage.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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