Low-dose norepinephrine to prevent blood pressure drops during emergency abdominal surgery
Treatments studied
Part of Digestive system, Infections clinical trials.
This study tests whether giving a low dose of norepinephrine (a blood pressure-supporting medication) through an IV during anesthesia can prevent dangerous blood pressure drops in patients having emergency surgery for peritonitis (a serious abdominal infection). The goal is to keep patients safer during the critical moments right after anesthesia starts.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You need emergency surgery for peritonitis (abdominal infection) under general anesthesia
- Your blood pressure is stable enough before surgery (at least 65 mmHg mean arterial pressure) without current blood pressure support medications
- You do not have severe heart disease, heart failure, or serious heart rhythm problems
- You are not allergic to norepinephrine, propofol, fentanyl, or rocuronium (the medications used in this study)
- You are willing to have an arterial catheter (a small tube in your artery to monitor blood pressure closely)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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