Clin2
NCT07531979Likely a fitNot yet recruiting

New Drug Combination for Advanced Esophageal Cancer

ESCCTislelizumabChemotherapyBecotatug VedotinEGFR ADCPD-1 Inhibitor

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests a new combination of three drugs (becotatug vedotin, tislelizumab, and chemotherapy) for esophageal squamous cell carcinoma—a type of cancer in the food tube. The study aims to see if this combination works better than standard treatments.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
93 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Diagnosed with locally advanced or metastatic esophageal squamous cell carcinoma confirmed by biopsy
  • No previous chemotherapy or immunotherapy for esophageal cancer (unless it was more than 6 months ago and the cancer came back)
  • Good overall health with ability to care for yourself (ECOG score 0 or 1)
  • Adequate blood cell counts, kidney function, and liver function based on recent blood tests
  • Willing to use birth control during the study and for 8 weeks after the last dose
  • Expected to live at least 6 months and able to attend follow-up visits

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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