Microbiota Transplant for Cancer-Related Weight Loss

This trial tests whether fecal transplants (putting healthy donor bacteria into your gut) can help with side effects like diarrhea, constipation, or nausea caused by cancer treatments. It is for people with advanced gastrointestinal cancer who are about to start their fourth round of chemo or targeted therapy.

This trial tests a treatment called “washed microbiota transplant,” which transfers healthy gut bacteria to help relieve intestinal problems that started after cancer therapy. You might benefit if you’re an adult with certain ongoing stomach or bowel symptoms after standard cancer treatment, and your body is stable enough for the procedure.

This study looks at how changing the gut microbiome (gut bacteria) may help people with pancreatic cancer regain strength and slow or reverse cancer-related weight loss (cachexia). It also studies gut bacteria differences in people with pancreatic cancer who are losing weight versus those whose weight is stable, and in healthy volunteers.

This trial tests whether a fecal transplant (a stool donation from a healthy person) can help patients with advanced stomach cancer respond better to treatment. If you qualify, you would receive the transplant through a colonoscopy, possibly along with other standard therapies.

This trial tests whether “washed microbiota transplant” (a treatment using processed gut bacteria) can improve malnutrition in adults who developed it after certain upper gut surgeries. It may help by restoring helpful gut bacteria, but you must meet several medical and safety checks.

This study tests whether fecal microbiota transplantation (FMT) – transferring healthy gut bacteria via capsules – can help prevent or ease digestive side effects (like diarrhea or constipation) caused by cancer treatment for extrapulmonary neuroendocrine neoplasms. If you are experiencing such symptoms, this approach might improve your quality of life during treatment.