Cold Exposure Plus Immunotherapy for Advanced Solid Tumors
Part of Cancer clinical trials.
This study tests whether controlled cold exposure combined with PD-1/PD-L1 immunotherapy (checkpoint inhibitor drugs that boost your immune system) can help fight solid tumors better than immunotherapy alone. The cold exposure is meant to trigger immune responses that may make the immunotherapy work more effectively.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18–75 years old
- Confirmed solid tumor cancer (lung, melanoma, kidney, etc.) that your doctor plans to treat with PD-1/PD-L1 immunotherapy
- Good overall health (ECOG performance status 0–1), able to walk around and do light daily tasks
- No severe heart, lung, or blood vessel disease; no severe cold-related conditions like Raynaud's syndrome or cold urticaria
- If previously treated with immunotherapy, at least 4 weeks must have passed since your last dose, and past side effects must have improved
- Able to tolerate controlled cold exposure and willing to follow study procedures
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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