Clin2
NCT07543640Possibly a fitNot yet recruiting

Roflumilast for psoriasis in skin folds or on genitals

Flexural Psoriasis (Also Known as Inverse or Intertriginous Psoriasis) and Genital Psoriasis

Treatments studied

Part of Skin clinical trials.

This trial tests whether roflumilast cream can effectively treat psoriasis in skin folds or on the genitals for people who have not had success with other creams. If you have this type of psoriasis and other treatments haven't cleared it up, this study might be an option.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
56 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have psoriasis in skin folds or on the genitals that has not cleared up after using topical treatments for 4 to 6 weeks.
  • You have not taken any systemic psoriasis medication in the last 3 months.
  • You have not used any topical treatments for your psoriasis in the last 2 weeks before starting the study.
  • You are not pregnant or breastfeeding, and if you are a woman of childbearing age, you agree to use contraception.
  • You do not have major health conditions like heart, lung, kidney, liver, or stomach disease, or severe blood disorders.
  • You do not have erythrodermic or pustular psoriasis, or psoriatic arthritis.
  • You do not have other autoimmune diseases like lupus.
  • You do not have a history of cancer such as breast cancer or leukemia.
  • You have not received biologic therapy in the last 6 months.
  • You are not allergic to roflumilast or methotrexate.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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