Treatment
Roflumilast clinical trials
We’re tracking 11 recruiting studies that include Roflumilast, each written for real people, not researchers, below.
Recruiting studies
- NCT06977711RecruitingPhase 1
Testing a new drug combo for high-risk DLBCL
This trial is testing a new combination of drugs for people with a high-risk type of lymphoma called DLBCL who have not been treated before. It adds loncastuximab and roflumilast to the standard R-CHOP therapy to see if it works better at fighting the cancer.
San Antonio, TexasAges 18 years+ - NCT07560618RecruitingPhase 4
Testing a new cream for itch relief in atopic dermatitis
This study tests whether roflumilast cream (a new anti-inflammatory medication applied to the skin) can reduce the intense itching caused by atopic dermatitis (eczema). You'll track your itching daily using a smartphone app and visit the clinic to see if the cream helps over time.
Sacramento, CaliforniaAges 12 years+ - NCT07105254RecruitingPhase 2
Roflumilast foam study for children with vitiligo
This study tests a medicated foam (Roflumilast) in children with non-segmental vitiligo to see if it can improve skin color on the face and body. It is for patients aged 2 to 17 with small patches and at least some pigmented hair in the face patches.
Dallas, TexasAges 2–18 - NCT07263230RecruitingPhase 2
Roflumilast Foam for Hidradenitis Suppurativa
This study tests whether roflumilast foam (a prescription foam) is safe and can reduce inflamed bumps in people with mild-to-moderate hidradenitis suppurativa (HS) who do not have draining tunnels. Participants will stop other HS treatments during the trial.
Boston, MassachusettsAges 18 years+ - NCT06860958RecruitingPhase 3
Adding roflumilast to antidepressants for depression
This study tests if adding roflumilast, a medicine that reduces inflammation, can help people with major depression feel better when taken with their current antidepressant. It is for adults with moderate to severe depression.
TantaAges 18–65 - NCT07077902RecruitingPhase 2
Roflumilast foam for hidradenitis suppurativa
This study tests if a foam applied to the skin (roflumilast 0.3%) is safe and effective for treating hidradenitis suppurativa (HS). It may help people with mild to moderate HS who haven't had success with other treatments.
Covington, LouisianaAges 18–90 - NCT07233291RecruitingPhase 2
Roflumilast pills for moderate to severe psoriasis in adults
This study tests an oral medicine called roflumilast for adults with moderate to severe plaque psoriasis. It aims to see if the drug is safe and effective when taken by mouth, and you can join if you have not used other systemic treatments recently.
Al Mansurah, Dakahlia GovernorateAges 18 years+ - NCT07297602RecruitingPhase 2
Oral roflumilast for moderate to severe eczema in teens and adults
This study tests an oral medicine called roflumilast to see if it helps treat moderate to severe eczema in people aged 12 and up who haven't used other systemic treatments recently. It's a pilot study to check both safety and how well it works.
Al Mansurah, Dakahlia GovernorateAges 12 years+ - NCT07566351RecruitingPhase 2
Add-On Drugs for Rheumatoid Arthritis
This study tests whether two drugs—roflumilast and desloratadine—added to your current rheumatoid arthritis medications can reduce joint inflammation and pain. You'd take these as add-ons to your existing treatment to see if they help control your disease better.
Damietta, Damietta GovernorateAges 18–60 - NCT07632846RecruitingPhase 2
Roflumilast as add-on treatment for active rheumatoid arthritis
This study tests whether adding roflumilast, a new medication, to your current rheumatoid arthritis treatment can help reduce joint inflammation and improve your symptoms. You would take it alongside methotrexate, a common RA medication you may already be using.
Al MansurahAges 18–60 - NCT06643221RecruitingEarly Phase 1
Exercise as a booster for cell therapy treatments
This trial tests whether exercise and a heart medicine called isoproterenol can help your immune system work better with donor cell therapies. It may show how to make these treatments more effective.
Tucson, ArizonaAges 21–55
What Roflumilast is being studied for
Conditions with recruiting Roflumilast studies.
Common questions
- Are there clinical trials studying Roflumilast?
- Yes. Clin2 currently lists 11 recruiting studies that include Roflumilast, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Roflumilast trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Roflumilast an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Roflumilast or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.