Cream for psoriasis affecting skin and nails
Part of Bones, joints & muscles, Skin clinical trials.
This study tests a new prescription cream called roflumilast to see if it helps with both skin plaques and nail psoriasis. If you join, you'll apply the cream to affected areas and be monitored to see how well it works and if it's safe.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 12 years old or older.
- You need to have had stable psoriasis, including nail symptoms, for at least 6 months.
- At least 3 fingernails must be affected by nail psoriasis.
- You must be able to avoid certain nail treatments and products (like gels, acrylics, or hardeners) during the study.
- You cannot have used PDE4 inhibitor treatments (like apremilast or oral roflumilast) in the past 6 months.
- You must not have severe kidney or liver problems, HIV, or a history of severe depression or suicidal thoughts.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a medical device called PROXERA PSOMED 30 to see if it safely and effectively treats nail psoriasis (psoriasis affecting fingernails or toenails). If you have nail psoriasis, this trial may help determine whether this device works better than current treatments.
This study tests a medicated foam (Roflumilast) in children with non-segmental vitiligo to see if it can improve skin color on the face and body. It is for patients aged 2 to 17 with small patches and at least some pigmented hair in the face patches.
This trial tests whether roflumilast cream can effectively treat psoriasis in skin folds or on the genitals for people who have not had success with other creams. If you have this type of psoriasis and other treatments haven't cleared it up, this study might be an option.
This study tests an oral medicine called roflumilast for adults with moderate to severe plaque psoriasis. It aims to see if the drug is safe and effective when taken by mouth, and you can join if you have not used other systemic treatments recently.
This study tests a new foam (roflumilast) applied to the skin to treat seborrheic dermatitis, a condition causing red, flaky patches usually on the scalp or face. It aims to see if the foam reduces redness and scaling better than a placebo.
This trial tests a new cream form of apremilast, a medicine usually taken as a pill, for people with plaque psoriasis covering less than 10% of their body. The goal is to see if the cream is safe and effective in reducing psoriasis symptoms.
Hear when a new Nail Psoriasis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.