Pain Relief After Hip Replacement Surgery
Treatments studied
Part of Bones, joints & muscles, Pain clinical trials.
This study tests whether a new pain medication called TRD205 works well and is safe for people recovering from hip replacement surgery. If it works, it could offer better pain control after your operation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for elective (planned) hip replacement surgery under general anesthesia
- You are between 18 and 80 years old with a healthy weight range (BMI 18–32)
- You are in good overall health (ASA status I or II, meaning no serious heart, liver, or kidney disease)
- You can take pills by mouth after surgery and understand pain rating scales
- You have not had hip surgery on the same side in the past year, and no major drug or alcohol use in the past year
- You are not allergic to TRD205, celecoxib (an anti-inflammatory), or related pain medications
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new painkiller pill (TRD205) for people having hip replacement surgery. The goal is to see if it's safe and works well for controlling pain after surgery.
This research study tests a combination of non-narcotic pain medicines (like Tylenol, Celebrex, and others) to see if they can control pain after hip replacement surgery while reducing the need for strong opioids. The goal is to help patients recover with fewer side effects and less risk of opioid dependence.
This study compares two common numbing medicines used during hip replacement surgery to see which one provides better pain relief after surgery. You'll receive spinal anesthesia (numbing injected near your spine) with either ropivacaine or bupivacaine, and researchers will track how long the pain relief lasts.
This trial compares two nerve-blocking techniques to reduce pain after hip replacement surgery. Both methods use numbing medication around specific areas near your hip to help you feel more comfortable after the operation.
This study compares different ways to manage pain during and after hip replacement surgery in older adults. Researchers will test whether a spinal injection with morphine works better than a nerve block (with or without a steroid), aiming to find the approach that gives the best pain relief with fewer side effects.
This trial tests if using fewer opioids after hip replacement surgery can still control pain well. It uses a specific type of hip replacement called anterior total hip arthroplasty and aims to help patients recover with less reliance on strong pain medicines.
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