Testing MG-K10 for chronic hives that don't respond to allergy pills
Treatments studied
Part of Immune system & allergy, Skin clinical trials.
This study tests whether a new drug called MG-K10 can help people with chronic hives (itchy welts) that haven't improved with standard allergy medications. MG-K10 works differently than regular allergy pills, targeting a specific immune pathway that causes hives.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 12–75 years old and weigh at least 30 kg (about 66 lbs)
- Have had chronic hives with itching and welts for at least 6 months, even while taking allergy pills
- Have active hives right now (confirmed by a scoring system within the past week)
- Willing to keep taking your current allergy medication at a stable dose during the study
- No active or untreated tuberculosis, serious infections, or certain liver/kidney/blood count problems
- Not pregnant, breastfeeding, or planning to become pregnant during the study and 6 months after
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new injection (CM512) for people with chronic spontaneous urticaria, also known as chronic hives. If you have had itchy hives for at least 6 weeks despite taking regular antihistamines, this study may help find a new treatment option.
This study tests a new oral medication (TLL-018) for people with chronic spontaneous urticaria (hives that last more than 6 weeks) who still have symptoms despite taking antihistamines. The goal is to see if the drug can reduce itching and hives better than placebo.
This trial tests a new medication called THB335 for people with chronic spontaneous urticaria (CSU), which causes hives and itching for months without a clear cause. The study will see if the drug can reduce hives and itching better than a placebo (a pill with no active medicine).
This study tests a new drug, TLL-018, for people with moderate-to-severe chronic hives (CSU) that don't respond well to standard antihistamines. The goal is to see if it works quickly to reduce itching and hives.
This study tests whether a bacterial lysate medicine (OM-85) combined with allergy medication can better control chronic hives in people whose regular allergy pills aren't working well enough. You'll be observed over time to see if this combination is safe and effective.
This trial tests a new tablet (Alpha-0261) for chronic spontaneous urticaria (long-lasting hives without a clear cause). It aims to see if the drug is safe and tolerable. Part 1 includes people with chronic hives, and Part 2 looks at how food affects the drug in healthy adults.
Hear when a new Chronic Spontaneous Urticaria (CSU) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.