Axillary lymph node surgery choices for HER2+ and triple-negative breast cancer
Part of Cancer, Skin clinical trials.
This study examines the best surgical approach for removing underarm lymph nodes in patients with HER2-positive or triple-negative breast cancer who have received chemotherapy before surgery and still have cancer in their lymph nodes. The goal is to understand whether removing more lymph nodes improves outcomes for these patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Diagnosed with stage I–III HER2-positive or triple-negative breast cancer (not spread to other organs at diagnosis)
- Received chemotherapy before surgery to shrink the tumor
- Had sentinel lymph node surgery or similar imaging-guided lymph node removal procedure
- Cancer cells larger than 2 mm found in lymph nodes after chemotherapy and surgery
- Surgery completed by October 2024 with at least 1 year of follow-up information available
- Not a hormone-receptor-positive breast cancer (unless hormone receptors are very low)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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