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NCT07549282Possibly a fitNot yet recruiting

Nasal sedative to protect the heart during angioplasty

Coronary Heart DiseaseMyocardial InjuryMyocardial InfarctionDexmedetomidine

Treatments studied

Part of Heart & circulation clinical trials.

This study tests whether a sedative given as a nasal spray before a heart procedure (angioplasty) can reduce heart damage. It may help people with heart disease who are having this procedure.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
140 people
Ages
18 years to 85 years
Study type
Interventional

Who can take part

  • You are between 18 and 85 years old.
  • You have coronary artery disease (narrowing of heart arteries) and are scheduled for a non-emergency angioplasty (a procedure to open blocked arteries).
  • You have mild to severe, but stable, other health conditions (like diabetes or high blood pressure) that are managed.
  • You are not taking certain medicines (like clonidine or tricyclic antidepressants) within a week of the procedure.
  • You do not have severe heart problems (like very weak heart pumping), uncontrolled high or low blood pressure, sleep apnea, or severe liver or kidney issues.
  • You are not pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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