Nasal sedative for heart protection during coronary stent procedure
Treatments studied
Part of Heart & circulation clinical trials.
This study tests whether a sedative given as a nasal spray (called dexmedetomidine) can help protect your heart during a planned procedure to open blocked heart arteries. If you are having this procedure, the medication may reduce the risk of heart damage afterward.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 45 and 85 years old.
- You have coronary artery disease (blocked heart arteries) and are scheduled for a planned procedure to open those blockages (called a percutaneous coronary intervention, or PCI).
- You do not have certain heart rhythm problems like a very slow heartbeat or certain heart blocks that would make the study drug unsafe.
- Your heart is pumping well enough (with an ejection fraction of 40% or higher) and you are not in severe heart failure.
- You do not have sleep apnea or a body mass index (BMI) over 30.
- You are not pregnant or nursing, and you have no severe liver or kidney problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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