Oxytocin and self-compassion training for borderline personality disorder
Treatments studied
Part of Mental health clinical trials.
This study tests whether oxytocin (a hormone given as a nasal spray) combined with training in self-compassion can help people with borderline personality disorder, especially those who are very self-critical. You would receive the oxytocin spray and participate in self-compassion training sessions over several weeks.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with borderline personality disorder (BPD) using two specialized diagnostic interviews
- You are between 18 and 50 years old
- You have previously completed dialectical behavior therapy (DBT) or DBT skills training for your BPD
- You score higher than 12 on a self-criticism scale, meaning you struggle significantly with harsh self-judgment
- You are currently on a stable mental health medication plan that you can maintain without changes during the study
- You cannot have other serious mental health conditions, certain medical conditions (epilepsy, kidney failure, heart failure), or take medications that interfere with oxytocin
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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