CD-19 T-cell therapy for relapsed B-cell leukemia in teens and adults
Part of Blood & lymphatic, Cancer clinical trials.
This study tests a new engineered cell therapy (CD-19 t-haNK) designed to fight back B-cell acute lymphoblastic leukemia (a blood cancer) in patients whose cancer has returned or stopped responding to standard treatment. The therapy uses specially modified immune cells to target and destroy leukemia cells.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 12 years old
- Your leukemia has come back after going into remission or has not fully responded to initial treatment
- Your leukemia is confirmed by biopsy or blood tests
- Your heart, liver, and kidneys are working well enough (based on blood tests)
- You are willing to have a spinal tap (lumbar puncture) for testing and chemotherapy delivery into your spinal fluid
- You can attend study visits and follow all study procedures
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is testing a new CAR-T cell therapy (Senl_B19) for children and young adults with B-cell acute lymphoblastic leukemia (B-ALL) that has returned or not responded to treatment. It targets a protein called CD19 on leukemia cells to help your immune system attack the cancer.
This early-phase trial tests a personalized cancer treatment using your own immune cells (called CAR T-cells) to target and kill leukemia cells that have a specific marker (CD19). It may be an option for adults with B-cell acute lymphoblastic leukemia (B-ALL) who haven't had this type of therapy before.
This Phase 2 trial studies CD19 “redirected” cells made from your own blood to treat certain high-risk or relapsed B-cell acute lymphoblastic leukemia (B-ALL). It may help by targeting cancer cells that carry a protein called CD19.
This early-stage trial tests a personalized immune-cell treatment called CNCT19 in children and teens whose leukemia (ALL) has come back or not responded to prior therapy. It may help the immune system recognize and attack leukemia cells that carry CD19.
This trial tests a new type of CAR-T cell therapy (called universal CAR-T) that targets CD19 and CD20 markers on cancer cells. It is for people aged 12 to 75 with B-cell acute lymphoblastic leukemia that has not responded to standard treatments or has come back after treatment.
This early-phase trial tests an injected “CAR T” cell therapy made to attack CD19-positive blood cancers that have come back or did not respond. If you qualify, the study checks whether the treatment can help control the cancer and is safe enough to study further.
Hear when a new B-ALL trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.