Elacestrant for advanced ER+ HER2- breast cancer with ESR1 mutation
Treatments studied
Part of Cancer, Skin clinical trials.
This trial tests elacestrant, a new hormone therapy drug, in women whose advanced or spread breast cancer has stopped responding to first-line hormone treatment. The drug is designed to work against a specific genetic change (ESR1 mutation) that can develop in these cancers.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Postmenopausal woman, age 18 or older
- Advanced or metastatic ER+ HER2- breast cancer confirmed by biopsy
- Cancer progressed after first-line hormone therapy plus CDK inhibitor (a type of targeted drug)
- Able to perform light activities with minimal limitations (ECOG score < 2)
- No prior chemotherapy for advanced/metastatic breast cancer
- Not enrolled in another interventional trial within 30 days
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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