Clin2
NCT07568496Possibly a fitRecruiting

Nerve block for migraine with medication overuse headache

Migraine DisordersMedication Overuse HeadacheGreater Occipital Nerve Block

Part of Brain & nervous system clinical trials.

This study tests a nerve block injection at the back of the head to see if it can reduce migraines in people who also have headaches from overusing pain medication. It aims to provide a new treatment option for this difficult-to-treat condition.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
130 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You have been diagnosed by a doctor with migraine with medication overuse headache.
  • You are not allergic to lidocaine or corticosteroid medicines.
  • You have not had surgery on your skull.
  • You are not pregnant and are not planning to become pregnant during the study.
  • You are not currently using or planning to use CGRP-targeted therapies or Botox injections for your headaches.
  • You do not have uncontrolled depression or psychosis, and you do not have bleeding disorders.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06432127Not yet recruiting· Phase 4
Nerve block for migraine prevention

This study tests whether an ultrasound-guided nerve block at the back of the neck can help prevent migraine headaches. It may be an option for people who haven't found relief with standard preventive medications or who can't take them.

Bangkok
NCT07535723Not yet recruiting
Botulinum toxin or occipital nerve block for chronic migraine

This trial tests two treatments for chronic migraine: botulinum toxin injections and a nerve block at the back of the head. The goal is to see if these treatments can reduce headache days and improve quality of life.

Al Fayyum
NCT07347067Recruiting
Trigger point injections for chronic migraine

This study tests if injecting medication into specific painful spots in your muscles (called trigger points) can help reduce chronic migraine pain. It may be an option if you've tried other treatments but still have significant pain.

Beijing, Beijing Municipality
NCT07360782Recruiting
Personalized nerve treatment for medication overuse headache

This trial tests a treatment called personalized pulsed radiofrequency, which uses gentle electrical pulses on a nerve at the back of your head to help reduce headaches caused by using too much pain medication. It is designed for people who have been diagnosed with Medication Overuse Headache and want a non-drug option.

Ankara
NCT07170111Not yet recruiting
Nerve block treatment for migraine headaches

This study looks at whether a nerve block injection at the back of the head (called a greater occipital nerve block, or GONB) helps people with migraine when other preventive treatments haven't worked. It aims to find out which patients respond best to this treatment.

Istanbul
NCT07763678Not yet recruiting· Phase 4
Nerve blocks for chronic migraine: adding ear nerve block

This study tests whether adding a block of the greater auricular nerve (a nerve near the ear) to the standard occipital nerve block (at the back of the head) provides more relief for chronic migraine than the occipital block alone. Both are simple injections guided by ultrasound, and the goal is to reduce headache days and intensity.

Hear when a new Migraine Disorders trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.