Nerve Block Injection for Migraine and Medication Overuse Headache
Part of Brain & nervous system clinical trials.
This trial tests whether a nerve-blocking injection in the back of the head can help people with migraine who are taking too much headache medication. The injection uses a steroid and local anesthetic to reduce nerve signals that cause migraine pain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with migraine with medication overuse headache (taking headache medication too frequently) by a neurologist
- You are not pregnant and do not plan to become pregnant during the study
- You have never had an allergic reaction to steroids or lidocaine (numbing medicine)
- You have not had surgery on your skull or head
- You do not have severe depression, psychosis, or uncontrolled mood disorders
- You do not have bleeding disorders or take blood-thinning medications that increase bleeding risk
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests whether an ultrasound-guided nerve block (an injection near the back of the head) can help prevent migraine headaches in adults who either haven't tried prevention before or have had trouble with standard medications.
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This trial tests two treatments—botulinum toxin injections and nerve blocks in the neck—to reduce migraine frequency in people who have migraines on 15 or more days per month. Either or both treatments may help prevent migraines.
This trial looks at how well people respond to treatment when their headaches are caused by taking too much pain medicine. It may help if you have migraines or tension headaches and you use triptans or NSAIDs often.
This trial tests a treatment called personalized pulsed radiofrequency, which uses gentle electrical pulses on a nerve at the back of your head to help reduce headaches caused by using too much pain medication. It is designed for people who have been diagnosed with Medication Overuse Headache and want a non-drug option.
This Phase 2 trial tests whether nerve block injections can reduce pain from episodic migraines. It may help some people who get frequent migraine attacks but are not also using certain migraine preventions or strong pain medicines.
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