Botulinum toxin and nerve blocks for chronic migraine
Treatments studied
Part of Brain & nervous system, Pain clinical trials.
This trial tests two treatments—botulinum toxin injections and nerve blocks in the neck—to reduce migraine frequency in people who have migraines on 15 or more days per month. Either or both treatments may help prevent migraines.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have chronic migraine: headaches on 15+ days per month for at least 3 months, with at least 8 days showing typical migraine symptoms
- You are 18 years or older
- Your current migraine prevention medication(s) have been stable for at least 2 months
- You have not received botulinum toxin or greater occipital nerve block injections for headache in the past 3 months
- You do not have a bleeding disorder or take blood thinners that would make nerve blocks unsafe
- You are not pregnant and do not have neuromuscular diseases like myasthenia gravis
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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