How Weight Loss Surgery Changes Hormones and Gut Health
Part of Hormones & metabolism clinical trials.
This study examines how endoscopic sleeve gastroplasty (a minimally invasive stomach-reduction procedure) affects hormones and the healthy bacteria in your gut. Researchers will track these changes to better understand how the procedure helps with weight loss and related health conditions.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18 or older
- BMI between 30 and 40 kg/m² (roughly 197–262 lbs for a 5'10" person)
- Doctor recommends endoscopic sleeve gastroplasty or surgical sleeve gastrectomy for you
- Able to undergo CT scans and imaging tests as part of the study
- Not currently taking weight-loss medications like GLP-1 drugs (semaglutide, tirzepatide)
- No previous stomach surgery or history of stomach cancer
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at factors that predict weight loss success after a non-surgical stomach reduction procedure (endoscopic sleeve gastroplasty). It may help if you have obesity-related health problems and have not succeeded with diet or lifestyle changes.
This study tests a less invasive procedure called endoscopic sleeve gastroplasty to help people with obesity lose weight. It's designed for people who have tried diet and exercise but still need help, and who either can't have or don't want weight-loss surgery.
This study compares two different techniques for a procedure that helps with weight loss by reducing stomach size using an endoscope. It aims to see which technique is more effective for people with obesity.
This study tests a weight-loss procedure called endoscopic sleeve gastroplasty (a stomach-reducing procedure done through a scope) in people with both obesity and inflammatory bowel disease (IBD). It aims to see if the procedure is safe and helpful for this group.
This trial tests a non-surgical procedure called Endoscopic Sleeve Gastroplasty (ESG) to help people with obesity lose weight. A doctor uses a thin tube with a camera to stitch your stomach smaller, so you feel full sooner.
This study tests a non-surgical procedure called an endoscopic sleeve (Endosleeve) to help with weight loss in people with obesity. It's done through a scope placed in your mouth and stomach—no cuts needed—and aims to shrink your stomach to help you feel full sooner and eat less.
Hear when a new Obesity (Disorder) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.