Clin2
NCT07578116Worth exploringRecruiting

Adding surgery and radiation for her2-positive breast cancer with a few spread spots

Anatomic Stage IV Breast Cancer AJCC v8Metastatic HER2-Positive Breast CarcinomaOligometastatic Breast Carcinoma

Treatments studied

Part of Cancer clinical trials.

This trial tests whether adding surgery and radiation to the usual HER2-targeted treatment helps people with breast cancer that has spread to a few spots. You must have HER2-positive cancer that is newly spread, and you must be able to receive radiation to all tumor sites.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
562 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must have breast cancer that has just been found, and it has spread to only 1 to 5 other spots in your body (not counting the breast).
  • Your cancer must be HER2-positive (a specific protein found in the tumor).
  • You must be 18 or older and able to do everyday activities with only minor help (performance status 0–2).
  • If you have had some treatment already, you can have had only 1 to 3 cycles (doses) of it.
  • You cannot have had radiation to your whole brain before the study, and you must be able to receive precision radiation to all tumor spots.
  • You must have at least stable disease (not getting worse) after 12–24 weeks of standard treatment to be in the main group.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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