Tested targeted radiation plus usual drug treatment in metastatic breast cancer

This trial tests whether giving radiation to a few growing spots (1-3) can let you stay on your current drug longer, instead of switching to a new one right away. It's for people with metastatic breast cancer whose disease has been stable for months but now shows limited progression.

This trial tests whether a precise radiation treatment (SBRT) can target a few growing spots of estrogen receptor-positive breast cancer that has spread to other parts of the body. It also uses a special PET scan (FES PET/CT) to see how well the cancer responds. The goal is to slow down the cancer and delay the need for stronger treatments.

This trial tests whether treating each spot of cancer that has spread (but only a few spots) with focused radiation can help control breast cancer. It aims to see if this approach can stop the cancer from growing further without needing strong whole-body treatments right away.

This Phase 2 study tests whether treating a small number of metastatic spots with a local approach (like targeted radiation, surgery, or ablation) can help people with ER/PR-positive breast cancer. It aims to help when the cancer has spread only to a few areas and has not significantly worsened after initial whole-body treatment.

This trial tests whether adding a precise, high-dose radiation (called SABR) to your current targeted therapy can control a few growing spots of advanced breast cancer better than switching to a different drug. It is for people with ER-positive, HER2-negative breast cancer whose cancer has been well controlled for at least 6 months but now has 1–5 spots that are starting to grow.

This trial studies a type of focused radiation given in smaller parts to treat bone metastases from breast cancer. It may help shrink tumors and improve control of pain or growth when standard treatments haven’t worked or surgery isn’t possible.