Steroid injection for leg pain caused by nerve pinching
Treatments studied
Part of Brain & nervous system, Pain clinical trials.
This study tests whether a steroid injection into the space around the spinal cord (epidural space) can relieve leg pain caused by a pinched nerve, a condition called sciatica. If the injection works, it may help reduce your pain without surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18–75 and able to read and understand English
- Leg pain from a pinched nerve (sciatica) lasting 6 weeks to 9 months
- MRI imaging that confirms the nerve pinching matches your symptoms
- Pain score in the affected leg must be worse than lower back pain
- Willing to track daily pain scores in a digital diary for 7 days before treatment
- Not planning spine surgery during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new medicine called C-1101, given as a shot into the spine, to see if it safely reduces pain from chronic sciatica. It is for people who have not gotten enough relief from standard treatments.
This study tests whether a specific back/nerve pain injection (an epidural injection) can help people with acute sciatica. You may qualify if your sciatica started a few weeks ago and your leg pain is still quite severe.
This study is testing how well and how safely steroid injections work for different types of back pain. If you join, you'll receive the injection as part of your care and fill out surveys about your pain and ability to do daily activities before and after.
This study is testing a treatment that involves an injection to reduce nerve-related leg and back pain. It looks at how much information about the procedure affects a patient's outlook and pain relief.
This trial compares ibuprofen alone versus ibuprofen plus dexamethasone (a steroid) for short-term relief of acute nerve-related low back pain that shoots into the buttock or leg. It aims to see which approach reduces pain and improves function after an emergency visit.
This study is testing whether changes in pain after a steroid injection into the spine can predict how well the treatment works. You may be eligible if you have a slipped disc in your lower back that causes at least moderate pain, and other treatments haven't helped enough.
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