Vortioxetine for Depression with Migraine
Part of Brain & nervous system clinical trials.
This study tests whether vortioxetine, a depression medication, can help people who have both depression and episodic migraine (recurring headaches). You'd take vortioxetine for depression while researchers track how it affects both your mood and migraine symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have been diagnosed with depression and started on vortioxetine within the past week
- You have episodic migraine (recurring headaches with or without aura, starting before age 50) confirmed by a headache specialist
- Your depression is moderate to severe (HAM-D score above 18—a standard scoring system)
- You are not taking other depression medications or migraine preventive drugs (like tricyclic antidepressants, CGRP antibodies, or gepants)
- You have no other significant chronic pain conditions like fibromyalgia or chronic low back pain, and no history of psychosis or bipolar disorder
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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