Testing Efgartigimod for Autoimmune Brain Inflammation
Part of Brain & nervous system, Immune system & allergy clinical trials.
This trial tests a medicine called efgartigimod to treat autoimmune encephalitis (AIE)—a rare condition where the immune system attacks the brain. The study enrolls children 12+ and adults to see if this drug can reduce symptoms and help recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 12 years old
- You have been diagnosed with possible or confirmed autoimmune encephalitis (AIE)
- You have not received certain blood-filtering treatments (PLEX) or immune infusions (Ig) for AIE in the past, or not in the last 3 months for other conditions (Part A only)
- You do not test positive for anti-MOG antibodies
- You have no major surgery planned during the study, except for AIE-related brain or chest tumors
- No active substance abuse or untreated psychiatric conditions unrelated to your AIE
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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