Vaccine response for older people on dialysis
Treatments studied
Part of Infections, Lungs & breathing clinical trials.
This study tests whether giving a low dose of the medicine sirolimus (rapamycin) before the flu or RSV vaccine improves the body's immune response in older adults on dialysis. It may help make vaccines work better for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are older than 60 years.
- You have end-stage kidney disease and receive dialysis at a center three times a week.
- You have not had a confirmed flu or RSV infection in the last 6 months.
- You are not currently taking certain drugs that suppress the immune system (like steroids, mycophenolate, azathioprine, or others).
- You have not had strong intravenous immune-suppressing drugs in the last 6 months.
- You do not have certain conditions like lung disease, recent cancer, or severe high cholesterol that could be worsened by sirolimus.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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