Clin2
NCT07589322Possibly a fitRecruiting

How GLP-1 drugs reshape fat and metabolism

Obesity and Metabolic Syndrome

Part of Hormones & metabolism clinical trials.

This study compares how a GLP-1 medication (a drug that helps control blood sugar and weight) changes the way your body stores and uses fat. Researchers will use imaging scans to see these changes over time in people with metabolic syndrome—a cluster of health conditions including high blood pressure, high cholesterol, and excess weight.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
120 people
Ages
20 years to 65 years
Study type
Interventional

Who can take part

  • Age 20–65 years old
  • BMI of 27 or higher (overweight or obese) with metabolic syndrome (high blood pressure, high cholesterol, and/or high blood sugar in a pattern doctors recognize)
  • Stable doses of blood-pressure or cholesterol medications for at least 3 months
  • No personal or family history of medullary thyroid cancer, MEN2 syndrome, pancreatitis, or diabetes
  • Kidney and liver function well enough to safely participate (eGFR ≥30, no severe liver disease)
  • No recent heart attack, stroke, or heart procedure in the last 3 months

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07740291Recruiting
Tirzepatide and lifestyle study for weight loss

This trial compares two ways to manage weight: taking a GLP-1 medication (like tirzepatide or semaglutide) versus making lifestyle changes without medication. It will help researchers learn which approach works best for people with overweight or obesity.

Lubbock, Texas
NCT07832084Not yet recruiting· Phase 4
Comparing weight loss medication plans after GLP-1 therapy

This trial compares different ways to keep weight off after you've lost weight using a GLP-1 medication, like semaglutide or tirzepatide. It tests reducing your GLP-1 dose and adding other weight loss medications to help maintain your progress.

Pittsburgh, Pennsylvania
NCT07858864Recruiting
GLP-1 weight loss drugs and muscle health in obesity

This study looks at how GLP-1 receptor agonist drugs (used for weight loss) affect muscle mass and strength in people with obesity who do not have diabetes. It may help understand if these medications impact muscle health.

Istanbul, Kucukcekmece
NCT07021937Not yet recruiting· Phase 3
Brain changes and weight-loss medication for obesity

This study tests whether a weight-loss medication (a GLP-1 agonist) can change how the brain works and help with long-term weight control. It involves brain scans and a closely monitored treatment plan.

Aurora, Colorado
NCT07156331Not yet recruiting
Imaging study of diabetes drugs and body changes

This study is looking at how certain diabetes medications affect the body's makeup (like muscle and fat) and how the body works, using special imaging scans. It may help doctors understand these treatments better and could guide future care.

NCT06338553Recruiting· Early Phase 1
GLP-1 drug for early type 1 diabetes

This study tests whether a GLP-1 receptor agonist (a type of medicine that helps control blood sugar and appetite) can improve metabolic health in people with early type 1 diabetes. It may be an option if you have already taken teplizumab to delay the disease or were recently diagnosed with type 1 diabetes.

Nashville, Tennessee

Hear when a new Obesity and Metabolic Syndrome trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.