Weight loss drug effects on brain and blood vessels
Treatments studied
Part of Hormones & metabolism clinical trials.
This study tests whether a weight loss medication called semaglutide can improve brain and blood vessel health in people with overweight or obesity. It may help you understand if this treatment could benefit your overall health.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 35 and 55 years old.
- Your body mass index (BMI) is between 27 and 40 (for the weight loss group) or between 20 and 25 (for the lean comparison group).
- You are willing to inject the study medication yourself and follow the study schedule.
- You do not have type 2 diabetes, a neurological disorder, or a history of pancreatitis.
- You have not had significant weight changes (more than 5 kg) in the last 90 days.
- You are not currently taking other weight loss medications or have had bariatric surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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