Testing a Drug to Reverse Muscle Relaxant Effects During Surgery
Treatments studied
This study tests a new medication called amogammadex that reverses the effects of muscle relaxants used during surgery. Researchers want to find the right dose of this drug to safely wake up your muscles after anesthesia.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18–60 and in generally good health (ASA physical status 1 or 2)
- Scheduled for about 2-hour surgery with specific muscle relaxants (vecuronium or rocuronium)
- BMI between 18–32 kg/m² and weighing at least 50 kg (men) or 45 kg (women)
- No serious heart, liver, kidney, or neurological conditions
- Willing to use reliable contraception and avoid pregnancy for 3 months after the study
- No known allergies to anesthesia drugs or cyclodextrin (the drug's base ingredient)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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