Melasma treatment: comparing two skin lightening options
Part of Skin clinical trials.
This study compares two treatments for melasma: injecting tranexamic acid into the skin versus applying a mandelic acid facial peel. The goal is to see which one works better at lightening the dark patches on your face.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 45 years old.
- You must have melasma (dark patches) on your face.
- Your skin type should be type III to V on the Fitzpatrick scale (medium to dark skin tones).
- You must have had melasma for at least 3 months.
- You can't be pregnant or breastfeeding.
- You cannot have a history of blood clots or bleeding disorders.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two creams — metformin and tranexamic acid — to see which works better for melasma (dark patches on the face). If you qualify, you'll use one of the creams and your progress will be checked over time.
This study compares a metformin cream to a standard treatment (Kligman's regimen) for reducing melasma, a common skin condition causing dark patches on the face. It aims to find which treatment is more effective for women with this condition.
This trial tests two injectable treatments for melasma (dark patches on the face): platelet-rich fibrin, which uses your own blood cells to promote healing, and tranexamic acid, a medication that may reduce pigmentation. The study will compare which works better for women with mild to moderate melasma.
This study compares two topical creams — one with tranexamic acid and one with vitamin C (ethyl ascorbic acid) — to see which works better for treating melasma. If you have melasma and meet the health criteria, you may be able to join and receive one of these treatments.
This study tests whether a medicine called tranexamic acid, taken as a pill or used on the skin, can help fade melasma in women with darker skin types. It aims to find a safe way to improve skin color and is relevant to those looking for new melasma treatment options. The trial compares the treatment to another study treatment without medicine. Participation is open to women aged 30 to 60 with darker skin tones who are not pregnant and are not using certain other skin or hormone treatments.
This trial tests whether taking tranexamic acid (a medicine that helps reduce pigmentation) along with a skin treatment called microneedling is more effective for treating melasma than microneedling alone. It aims to help women with facial melasma achieve clearer, more even skin tone.
Hear when a new Melasma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.