Genetic testing to understand fetal birth defects
Part of Genetic & congenital, Women’s health & pregnancy clinical trials.
This study uses advanced genetic testing (whole genome sequencing) on tissue samples from fetuses with structural abnormalities detected on ultrasound. The goal is to identify genetic causes of birth defects to help with diagnosis and understanding of your baby's condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old and pregnant
- You are carrying one baby (not twins or multiples)
- Your baby is between 11 and 32 weeks of pregnancy and has a structural abnormality seen on ultrasound or MRI
- You plan to have an invasive test (like amniocentesis) or will have testing after birth, and agree to use leftover samples for this research
- You must sign consent forms and agree to provide tissue samples and medical information for the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study helps identify genetic causes of birth defects that weren't found by standard tests. Researchers use advanced genetic mapping to look for structural changes in DNA that might explain your baby's condition.
This trial uses genetic testing to better understand the cause of a newborn’s birth defect and to help doctors choose more personalized treatment. It may help families get clearer answers and more targeted care.
This study offers genetic sequencing to find the cause of certain serious fetal problems, such as structural anomalies, severe growth restriction, or unexplained pregnancy loss after 14 weeks. It aims to help families understand why the issue occurred and guide future care.
This study tests whether sequencing the genes of the fetus alongside the parents' genes can help find the cause of certain ultrasound abnormalities during pregnancy. If you are pregnant and your doctor has suggested genetic testing due to unusual findings on ultrasound, this study may help provide a more precise diagnosis.
This study tests a new blood test that can screen for genetic problems in babies during pregnancy. It may find more conditions than standard tests, especially for pregnancies with certain ultrasound findings or other risk factors.
This study looks at the genetic material in the fluid around the baby (amniotic fluid) and in the placenta to better understand complex heart defects in unborn babies. The goal is to find new clues that could help doctors care for these babies before and after birth.
Hear when a new Prenatal Diagnosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.