Genetic testing of fetal fluid for rare diseases after ultrasound concerns
Part of Genetic & congenital clinical trials.
This study uses advanced genetic testing on the fluid around the baby to look for rare diseases when an ultrasound shows possible problems. It aims to give more complete information to help you and your doctor make decisions during pregnancy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You and your partner must be at least 18 years old.
- The pregnancy must have an ultrasound finding (like extra fluid, joint contractures, or bone problems) that your care team has decided needs exome sequencing.
- The test will be done on a fluid sample from around the baby (amniocentesis), not on placenta tissue.
- You must attend a genetic counseling session and sign a consent form.
- You need to be covered by the French social security system.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a safer blood test to check for certain genetic disorders during pregnancy, instead of an invasive procedure like amniocentesis. It's for pregnant women who are at risk of passing on a known genetic condition.
This study looks at DNA patterns in fetuses or children with rare genetic conditions. It aims to better understand how these patterns relate to diseases that start before birth, which could help with diagnosis and future care.
This study is testing a non-invasive prenatal blood test (NIPD) that can check for certain serious genetic disorders in your baby, instead of using more invasive methods like amniocentesis. If you are at risk of passing on a severe genetic condition, this test may help you get answers safely.
This study uses advanced genetic testing (whole genome sequencing) on tissue samples from fetuses with structural abnormalities detected on ultrasound. The goal is to identify genetic causes of birth defects to help with diagnosis and understanding of your baby's condition.
This study tests a new blood test that can screen for genetic problems in babies during pregnancy. It may find more conditions than standard tests, especially for pregnancies with certain ultrasound findings or other risk factors.
This study looks at the genetic material in the fluid around the baby (amniotic fluid) and in the placenta to better understand complex heart defects in unborn babies. The goal is to find new clues that could help doctors care for these babies before and after birth.
Hear when a new Couples Eligible for Prenatal Exome Sequencing trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.